"Novel Methods and Emerging Targets in Drug Discovery & Patented Drug Development"
Announcement
POSTER PRESENTATION DATES
Scientific Program Has Been Published
The congress will be held on 19-21 October at the BAU -Beşiktaş Campus, İstanbul.
Congress Start Date
October 19, 2017
Congress Location
Istanbul - TURKEY
Organiser
Bahcesehir University
THE DEADLINE FOR ABSTRACT SUBMISSION AND EARLY REGISTRATION HAS BEEN EXTENDED UNTIL SEPTEMBER 1, 2017.











Scientific Program
19 OCTOBER 2017 – B CONFERENCE HALL, BESIKTAS, ISTANBUL


08:00 - 09:00 Registration
09:00 - 09:30 Opening Ceremony
09:30 - 10:15 Novel molecular mechanism of a purine analog, Clofarabine, as an inhibitor of cell surface protein CD99 Dr. AYKUT ÜREN (IS-1)


10:15 - 10:45 COFFEE BREAK


NANOBIOTECHNOLOGY FOR NOVEL DRUG DISCOVERY

Chairs: Dr. Giulia Morra, Dr. Aykut Uren
10:45 - 11:15 Drug delivery and gene silencing using DNA based nanocarriers Dr. MUSTAFA ÇULHA
(IS-2)
11:20 - 11:50 Cationic Ag2S Quantum Dots as New Generation Theranostic Nanoparticles Dr. FUNDA YAĞCI ACAR (IS-3)
11:55 - 12:15 -Identification of Cardiogenic and Hematopoietic MEIS Inhibitors that Enhance Cellular Proliferation and HDR Gene Expression
-Identification of Cas9 small molecule inhibitors
Dr. FATIH KOCABAŞ
(OP)


12:15 - 13:30 LUNCH BOX


THERAPEUTIC AGENTS AND THEIR INTER/INTRA MOLECULAR INTERACTIONS

Chairs: Dr. Mustafa Guzel, Dr. Thomas Mavromoustakos
13:30 - 14:00 Pharmacological manipulation of PML nuclear bodies in cancer treatment Dr. UMUT SAHIN (IS-4)
14:05 - 14:35 A systems pharmacology approach to understanding predicted drug mechanisms of action and therapeutic effects CAROLIN FINCH (CLARIVATE)
14:40 - 15:30 On inter- and intramolecular interactions: Affinities, free energy-, enthalpy-, entropy- and heat capacity changes – On their interpretation and how to they can be measured Dr. PETER VIKEGARD
(TA Instruments)


15:30 - 16:00 COFFEE BREAK


MOLECULAR MODELING STUDIES ON PROTEIN DYNAMICS and EMERGING TARGETS IN DRUG DISCOVERY

Chairs: ADr. Umut Sahin; Dr. Mustafa Culha
16:00 - 16:30 Global Protein Dynamics in Function Dr. TURKAN HALILOGLU (IS-5)
16:30 - 17:00 Emerging targets in patented drug discovery –A case study using the Integrity database CAROLIN FINCH (CLARIVATE)
17:00 - 17:30 Molecular Insights for Resistance Conferring Mutations in Competitive Inhibition Dr. CANAN ATILGAN
(IS-6)
17:30 - 18:00 Modulation of the conformational cycle of Hsp70: a computational study Dr. GIULIA MORRA
(IS-7)
18:00 - 20:00 POSTER PRESENTATIONS-1 (PP-01 / PP-72)


20 OCTOBER 2017, FRIDAY - B CONFERENCE HALL, BESIKTAS, ISTANBUL


PROTEIN STRUCTURE AND FUNCTION

Chairs: Dr. Aykut Uren, Dr. Ivet Bahar
09:00 - 09:30 Information Transfer in Proteins and Allosteric Drug Design Dr. BURAK ERMAN
(IS-9)
09:35 - 10:00 Conformational sampling and ensemble docking for highly flexible and supramolecular structures Dr. PEMRA DORUKER
(IS-10)
10:05 - 10:35 Differential Activity of Mitochondria Targeting Photosensitizers Dr. ENGIN UMUT AKKAYA
(IS-11)


10:35 - 11:00 COFFEE BREAK


MD SIMULATIONS AND NMA APPLICATIONS

Chairs: Dr. Esin Aki Yalcin; Dr. Ismail Yalcin
11:00 - 11:30 Modeling and Simulations of Neurotransmission by Dopamine Transporters Dr. IVET BAHAR (IS-12)
11:35 - 12:00 Investigation of the Effect of Dimerization on the Functional Dynamics of Neurotransmitter: Sodium Symporters Dr. MERT GUR (IS-8)
12:00 - 12:15 On the Understanding of PDE Inhibitors-hERG K+ Ion Channel Interactions and Computational Design of Novel, Potent and Safe PDE5 Inhibitors GULRU KAYIK (OP)


12:15 - 13:30 LUNCH BOX


ANALYSIS OF PROTEIN/PROTEIN AND DRUG/PROTEIN INTERACTIONS

Chairs: Dr. Sebahattin Cirak; Dr. Mustafa Guzel
13:30 - 14:00 Allosteric Drugs that Target Ion Channels and GPCRs Dr. DIOMEDES LOGOTHETIS (IS-14)
14:05 - 14:35 Extraordinary Cytotoxic Activity a Natural Product (Pristimerin) on Breast Cancer In vitro and In vivo Dr. ENGIN ULUKAYA
(IS-15)
14:40 - 15:10 Epigenetic mechanisms of therapy resistance in cancer Dr. TUGBA BAĞCI ÖNDER (IS-16)
15:10 - 15:30 Membrane transporters in anti-cancer drug development and drug response Dr. SELVI DURMUS ERIM (IS-17)


15:30 - 15:50 COFFEE BREAK


STRUCTURE-ACTIVITY RELATIONSHIP STUDIES AND ACTIVE INGREDIENTS

Panel Chairs: Dr. Orkide Coskuner Weber, Dr. Diomedes Logothetis
15:50 - 16:20 Structure-Activity Relationships Analysis of Some Benzazoles as Topo II Enzyme Inhibitors Dr. ISMAIL YALCIN
(IS-18)
16:20 - 16:50 Drug Design Studies of Some Heterocyclic Compounds Active in Hospital-Acquired Infections Dr. ESIN AKI YALCIN
(IS-19)
16:50 - 17:20 Overcome of the Drug Undesired High Lipophilicity Dr. THOMAS MAVROMOUSTAKOS
(IS-20)
17:20 - 17:40 Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents Dr. CEYDA ACILAN AYHAN
(IS-21)
17:40 - 18:10 Precision medicine for muscular dystrophies Dr. SEBAHATTIN CIRAK (IS-22)
18:10 - 18:25 1,3,4-Thiadiazole derivatives caused apoptosis/necrosis inducing cell cycle arrest and suppressing pro-survival Akt activity in glioma and lung adenocarcinoma cells Dr. GULSEN AKALIN CIFTCI (OP)
18:25 - 18:40 The Inhibitory Effects of Capecitabine Derivatives on Thymidylate Synthase: A Molecular Docking Approach Dr. MAHMOUD MIRZAEI (OP)
18:40 - 18:55 Umbelliferone: A Small and Bioactive Molecule KERIMAN GUNAYDIN (OP)
19:00 - 20:15 POSTER PRESENTATIONS-II (PP-73 / PP-143)


21 OCTOBER 2017, SATURDAY - B CONFERENCE HALL, BESIKTAS, ISTANBUL


APPLICATIONS OF MOLECULAR MODELING APPROACHES ON PROTEIN-LIGAND INTERACTIONS

Chairs: Dr. Pemra Doruker, Dr. TURKAN HALILOGLU
09:00 - 09:30 Assessing Protein-Ligand Binding Modes for Known PDE4b Inhibitors Dr. VIKTORYA AVIYENTE (IS-23)
09:35 - 10:05 Understanding Differential Selectivity of Arrestins toward the Phosphorylation State of G-protein-coupled Receptors Dr. OZGE SENSOY (IS-24)
10:05 - 10:30 Discovery of Novel AT1 Ligands Using Structure and Ligand-based Drug Designing Techniques Dr. SERDAR DURDAGI
(IS-25)


10:30 - 11:00 COFFEE BREAK


CHEMICAL BIOLOGY AND DRUG DESIGN

Panel Chairs: Dr. Ismail YALCIN, Dr. Esin AKI YALCIN
11:00 - 11:30 Drugging ion channels as anti-metastatic targets in human cancers Dr. MUSTAFA DJAMGOZ (IS-26)
11:35 - 12:05 Diagnostic and therapeutic implications of omic approaches in lymphoid malignancies towards personalized medicine Dr. CAN KUCUK (IS-27)
12:05 - 12:30 ETS Transcription Factors - Critical Regulators of Brain Tumor Initiating Cell Proliferation vs Neurodegeneration? Dr. ISIL KURNAZ (IS-32)


12:30 - 13:30 LUNCH BOX


NANOTECHNOLOGY IN DRUG DESIGN

Panel Chairs: Dr. Yongsoo PARK, Dr. Adriano Mollica
13:30 - 14:00 Diabetes and Obesity: Silent Killers Dr. MUSTAFA GUZEL
(IS-29)
14:00 - 14:30 Phthalocyanine-based photosensitising nanoparticles Dr. FABIENNE DOUMOLIN (IS-30)
14:30 - 14:50 Nanotechnology in Ocular Drug Delivery Dr. MELIKE GEDAR
(IS-31)
14:50 - 15:05 Mechanism of the prenylation of L-tryptophan catalyzed by fgapt2: a computational study DORIAN ACEVEDO (OP)
15:05 - 15:20 Doxorubicin Loaded Carbon Nanotubes as Multimodal Nanocarriers for Cancer Treatment MEHDI MERAN (OP)
15:20 - 15:35 In vitro Biocompability of p-tert-butylcalix[4]arene on L-929 by Real Time Cell Analysis NOORA OMAR (OP)


15:35 - 16:00 COFFEE BREAK


THERAPEUTIC ACTIVITIES OF SMALL MOLECULES

Panel Chairs: Dr. Engin ULUKAYA, Dr. Mustafa CULHA
16:00 - 16:30 A Novel putative AT1 receptor inhibitor as a potential chemotherapeutic agent Dr. TIMUCIN AVSAR
(IS-28)
16:35 - 17:00 MicroRNA exocytosis by vesicle fusion as a novel neuromodulator Dr. YONGSU PARK (IS-33)
17:00 - 17:20 Design of the β-sheet ARC repressor mimetics: conformational analysis and binding properties of linear and cyclic peptides Dr. ADRIANO MOLLICA (IS-34)
17:20 - 17:40 Drug development status in Turkey and R&D Incentives in Turkey SIRIN DEHA (IS-35)
17:40 - 17:55 Study on the Protein Secondary Structure Analysis with ATR FT-IR Dr. YEKBUN ADIGUZEL (OP)
17:55 - 18:10 Ligand-centric Clustering of Proteins: A case-study on Sphingolipid Metabolic Pathway HAKIME OZTURK (OP)
18:10 - 18:25 Predicting the bioactive conformations of macrocycles ILKE UGUR (OP)
18:25 - 18:40 Potency of interleukin 8 blockade in prevention of liver cancer stem cell enrichment DENIZ CANSEN KAHRAMAN (OP)
18:40 - 18:55 Real-time Cell Analysis of the Inhibitory Effect of Calixarene on Adhesion and Proliferation of Breast Cancer Cells EMINE GOK (OP)


19:00 - 19:15 COFFEE BREAK


19:15 - 19:30 CLOSING CEREMONY AND POSTER AWARDS


21 OCTOBER 2017, SATURDAY – PARALLEL SESSIONS, BESIKTAS, ISTANBUL


PARALLEL SESSIONS, BESIKTAS, ISTANBUL

Chairs: Selvi Durmus Erim
09:00 - 09:15 The Effect of Milrinone on Cardiac Muscle After Ischemia-Reperfusion of Lower Extremities ESIN AK (OP)
09:15 - 09:30 Kinetic Resolution of Oxazinones with Squaramide Organocatalysts Dr. SERAP MERT (OP)
09:30 - 09:45 Discovery of New Azole Antifungals with Potent Activity against SUAT SARI (OP)
09:45 - 10:30 SHORT TALKS-I (10 Talks)
Identification of HDAC6 selective inhibitors via structure-based virtual screening and molecular dynamics simulation assay ABDULLAHI IBRAHIM UBA
In-Silico Design and Discovery of Novel Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK) Dr.MARIYA-AL RASHIDA
Molecular electrostatic potentials and HOMO-LUMO Studies of Angiotensin-converting enzyme (ACE) inhibitors for hypertension SYED MOHAMED ABUBACKER
Design of Potent Multi-target CAs inhibitors through Pharmacophore NUR GUREL
A Hybrid Approach for the Design, Synthesis and Anticancer Activity of Phenylaminopyrimidine Core Containing 2-Imino-4-thiazolidinone Derivatives ASLI DEMIRCI
Steered Molecular Dynamics Simulation for Efficient Ranking of Peptide - MHC Class I Binding Affinities ONUR SERCINOGLU
Computational Assessment Of Allosteric Mutations On The Dynamics Of Pdz Domains As Potential Therapeutic Targets NAZLI KOCATUG
Blue Luminescing Iron Oxide Nanoparticles for Gene and Drug Delivery Applications OZLEM UNAL
Calculation of Protein Mutability Landscape and Thereon Forecasting Evolutionary Pathways: Neuraminidase of H1N1 Virus as a Case Study ELIF CANDAS
Cytotoxic Activity of Lobothallia radiosa (Hoffm.) Hafellner in Human MCF-7 Breast Cancer Cells HATICE ESRA AKGUL


10:30 - 11:00 COFFEE BREAK


CHEMICAL BIOLOGY AND DRUG DESIGN

Chairs: Ozge Sensoy
11:00 - 11:15 In Vitro Cytotoxicity of Multiwalled Carbon Nanotubes as Protein Nanocarriers BIRCAN DINC (OP)
11:15 - 11:30 Elimination of Naproxen from Wastewaters with Various Polymeric Resins EBRU KURTULBAS (OP)
11:30 - 11:45 Synthesize of new Histamine Schiff base derivatives as an isoform-selective and potent carbonic anhydrase VII activators SULEYMAN AKOCAK (OP)
11:45 - 12:00 Expanding Boundary of Chemical Space with Virtual Reactions: Case Studies For Lead Generation and Lead Optimisation İSMAİL HAKKI AKGÜN (OP)
12:00 - 12:30 SHORT TALKS (10 short talks)  
Analysis of Protein-Ligand Interaction via Homology Modeling, Docking and Molecular Dynamics Techniques: Neuraminidase Protein (H1N1 influenza virus) as a Case Study GIZEM GOKCE
Modeling and Design of Controlled Drug Release Systems MERVENAZ SAHIN
Biomedical Applications of Electrospun p-tert-butylcalix[4]arene Nanofibers PEMBEGUL UYAR ARPACI
Computational Study on Controlled Release of Anti-Inflammatory Steroids from Mesoporous Metal-Organic Framework, MIL-101(Cr) MERVE AYVAZ KOROGLU
Role of BIP-SBDα subdomain to bind IRE1α: A coarse-grained molecular dynamic simulation and Free energy calculation study ZEKERIYA DUZGUN
Fabrication of Novel PEG based PDIBG Nanomaterials for Use of Drug Delivery Systems OLCAY MERT
Gold Substituted Schiff Bases Complexes NIHAL DELIGONUL
Insight to Understand Acetylcholinesterase Inhibitors: Computational Modeling Approaches ERICA CRISTINA MORENO NASCIMENT
New Pt(II) complexes containing 5-pyrimidinylferrocene: Synthesis, characterization and DNA binding abilities GULCE TASKOR
Interactions and Biological Evaluation of the complexed Candesartan and its prodrug Candesartan Cilexitine in Cyclodextrin with lipid bilayers SOFIA KIRIAKIDI


12:30 - 13:30 LUNCH BOX
This page has been visited             times.
 
Arkadyas Bilişim Hizmetleri
Copyright © 2017 Tüm Hakları Saklıdır